Cytochrome P450 is a family of enzymes that catalyze reactions involved in the metabolism of drugs and other xenobiotics. These enzymes are therefore important in pharmacologic and toxicologic studies, and information on their abundances is of value in the process of scaling in vitro data to in vivo …

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Amin Rostami, Chief Scientific Officer, Certara. Dr. Rostami leads a team of scientists working on extrapolation of in vitro data on drug metabolism to predict in vivo pharmacokinetics and pharmacodynamics in virtual patient populations. He has authored/co-authored around 115 peer-reviewed full articles. Dr.

Amin Rostami Chief Scientific Officer Professor Rostami is the Senior Vice President of Research & Development and Chief Scientific Officer at Certara. His mission is to ensure that the latest scientific advances in the field of biosimulation are incorporated into all of the drug development efforts by various pharmaceutical companies. Simcyp was founded in 2001 by Professors Geoff Tucker and Amin Rostami-Hodjegan as a spinout company from the University Of Sheffield, UK, creating a new technology, the Simcyp population-based Simulator. Simcyp joined with Certara in 2012 and has experienced dynamic growth, delivering groundbre Amin Rostami-Hodjegan, Masoud Jamei, & Thomas Polasek. 2 www.certara.com Physiologically-based pharmacokinetic modeling and simulation (PBPK M&S) •The authors thank Dr .Bob Powel and Prof Amin Rostami for their great help in the project design.

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Thomas M Polasek; Carl M Kirkpatrick; Amin Rostami-Hodjegan. 1 Nov 2018 Certara will host a Phoenix® User Group Meeting and lead 15 presentations said Certara Chief Scientific Officer Professor Amin Rostami. 12 Feb 2019 Professor Amin Rostami, Certara CSO, said: “We believe that MIPD will enable the healthcare industry to complete the transition from the  Professor Rostami is the Senior Vice President of Research & Development and Chief Scientific Officer at Certara. His mission is to ensure that the latest  3 Jul 2019 Director of Clinical Pharmacology, Certara I am a paid employee of Certara and South Australian Health.

Mr. Andrew Schemick, Chief Financial Officer, N/A, N/A, N/A. Prof. Amin Rostami PharmD, Ph.D., FCP  Amin is a Professor of Systems Pharmacology at the Centre for Applied at Simcyp Limited (a Certara Company), Amin leads a team of over 30 scientists  in. Uncharted Territories.

Rostami is recognized for his scientific leadership, original thinking, and commitment to knowledge sharing with his colleagues and students PRINCETON, NJ – Jan. 29, 2015 – Certara®, the global biosimulation technology-enabled drug development and drug safety consulting company, today announced that it has promoted Amin Rostami, Pharm.D., Ph.D. to senior vice president (SVP) of R&D and

Amin is Director of the Centre for Applied  2 May 2019 Copyright 2018 Certara, L.P. All rights reserved. Acknowledgements • Prof Amin Rostami-Hodjegan • Dr Masoud Jamei • Dr Khaled Abduljalil  To address that gap, MIDD software developer Certara L.P. genes by sequencing RNA in plasma exosomes.

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Author. Amin Rostami-Hodjegan 2 Certara, Blades Enterprise Centre, Sheffield , UK. PMID: 29023678; PMCID: PMC5813098; DOI: 10.1002/cpt.904 

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“This Amin Rostami-Hodjegan Prediction accuracy of pharmacokinetic parameters is often assessed using prediction fold error, i.e., being within 2, 3, or n-fold of observed values. Amin Rostami-Hochaghan (Participant) Impact : Cultural impacts, Economic impacts, Health impacts, Political impacts, Technological impacts Dosing for groups of patients who were not served previously by conventional drug information. Application of a physiologicallybased pharmacokineticmodel for the evalua-tion of single-pointplasma phenotypingmethod of CYP2D6 Rui Chen, Amin Rostami-Hodjegan, Haotian Wang, David Berk, Jun Amin Rostami Chief Scientific Officer Professor Rostami is the Senior Vice President of Research & Development and Chief Scientific Officer at Certara. His mission is to ensure that the latest scientific advances in the field of biosimulation are incorporated into all of the drug development efforts by various pharmaceutical companies. Professor Rostami is the Senior Vice President of Research & Development and Chief Scientific Officer at Certara. His mission is to ensure that the latest scientific advances in the field of biosimulation are incorporated into all of the drug development efforts by various pharmaceutical companies. Certara Reports Preliminary Fourth Quarter and Full Year 2020 Results and Issues Full Year 2021 Amin Rostami.
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2 www.certara.com Physiologically-based pharmacokinetic modeling and simulation (PBPK M&S) •The authors thank Dr .Bob Powel and Prof Amin Rostami for their great help in the project design. Thank Dr. Pavan Vajjah for his support in SimCYP simulation. Thank Dr. Ao Peng for his work in the bioassay. 0.00E+00 2.00E+00 4.00E+00 6.00E+00 8.00E+00 1.00E+01 1.20E+01 1.40E+01 0 24 48 72 96 120 144 168 192 216 240 (mg/L) Time (h) Biography. Professor Rostami is the Senior Vice President of Research & Development and Chief Scientific Officer at Certara.

Professor Rostami previously served as co-founder and vice president of R&D for Certara’s Simcyp Business Unit. Honor recognizes his advances in predicting in vivo drug responses based on in vitro data ST. LOUIS, MO – Feb. 26, 2014 – Certara™, a leading provider of Amin Rostami. Chief Scientific Officer. He joined Certara in 2012 as a co-founder of Simcyp Limited (a University of Sheffield spin-off which was acquired by Certara), Amin is also a Professor of Systems Pharmacology and the Director of the Centre for Applied Pharmacokinetic Research (CAPKR) Certara Leadership.
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He joined Certara in 2012 as a co-founder of Simcyp Limited (a University of Sheffield spin-off which was acquired by Certara), Amin is also a Professor of Systems Pharmacology and the Director of the Centre for Applied Pharmacokinetic Research (CAPKR) at the University of Manchester.

12 Jun 2019 accomplishments that the Simcyp team has achieved during the past 20 years,” said Certara Chief Scientific Officer Professor Amin Rostami.